HyPE : A Height-Controlled Hydrogel Polymerization Solution
In this application note, we demonstrate the utilization of HyPE, a photopolymerization solution, for the precise and localized control of the height of PEG-based hydrogels to make structures to grow cells in 3D. This approach, in synergy with our versatile bioengineering platform, PRIMO, provides an efficient means to produce hydrogel structures with precise dimensions and shapes. We subsequently apply this methodology to fabricate non-adhesive hydrogel constructs tailored to facilitate the growth of 3D cellular aggregates.
In this application note, we demonstrate the utilization of HyPE, a photopolymerization solution, for the precise and localized control of the height of PEG-based hydrogels to make structures to grow cells in 3D. This approach, in synergy with our versatile bioengineering platform, PRIMO, provides an efficient means to produce hydrogel structures with precise dimensions and shapes. We subsequently apply this methodology to fabricate non-adhesive hydrogel constructs tailored to facilitate the growth of 3D cellular aggregates.